SF · JUNE 5, 2026 · 1-6 PM PST

Closing the Loop SF 2026

When
June 5, 2026
1-6 PM PST
Where
Timber + Tide
South San Francisco
Register → Read the thesis
Agent
PHYLO
Design
ONAVA
Validate
ADAPTYV
Reagent
MONOD
Measure
GATOR
The Measurement Layer ◯ Closing the Loop ◯ The AI-Native Lab ◯ The Measurement Layer ◯ Closing the Loop ◯ The AI-Native Lab ◯ The Measurement Layer ◯ Closing the Loop ◯ The AI-Native Lab ◯
01 · The Thesis

The demo era is over.

Generative protein design has crossed a threshold. The best AI methods now produce functional candidates at rates that were unimaginable two years ago.

Which means design is no longer the bottleneck. The loop is. Every step has to produce signal clean enough for the next cycle to learn from. Design. Expression. Characterization. Analysis. When any link breaks, models get confident on noise, the next round is worse than the last, and the whole stack quietly degrades.

The teams shipping drugs in 2026 aren't winning on model size. They're winning on loop discipline.

Tight coupling between design and bench. Fast, clean characterization. Data the next training run can actually use. That's the work.

On June 5, four of the teams who've figured this out come together for one focused afternoon. No hype. No vendor pitches. Just the people doing the work, talking about what closes, and what doesn't.

02 · Speakers

Four talks. One loop.

Kexin Huang
Keynote · Agent Layer
Kexin Huang
Phylo · Co-founder
"The New Way Biologists Work." A live demo of Biomni Lab and the vision for agent-native pharma.
Sharrol Bachas
Design Layer
Sharrol Bachas, PhD
Onava · Founder & CSO
"Designing Functional Proteins with AI." Tightly coupling generative models to rapid experimental feedback.
Ron Gill
Validation Layer
Ron Gill, PhD
Adaptyv Bio · Innovation Manager
"Closing the Loop." Ultra-fast wet-lab validation for AI-guided protein design, with EGFR competition results.
MB
Reagent Layer
Monod Bio
Speaker TBA
"AI-Designed Biosensors on Gator." What happens when the reagents themselves are computationally engineered.
03 · Agenda

A focused afternoon.

1:00-1:15
Welcome & FramingWhy this room, why now. The measurement layer thesis.
Hong Tan · Gator Bio
1:15-1:50
Designing Functional Proteins with AIAI–human–lab-in-the-loop protein design at Onava.
Sharrol Bachas · Onava
2:00-2:50
Keynote: The New Way Biologists WorkBiomni Lab demo and the case for agent-native pharma.
Kexin Huang · Phylo
2:50-3:30
Closing the LoopUltra-fast wet-lab validation + EGFR competition results.
Ron Gill · Adaptyv Bio
3:30-4:00
Break & TabletopsCoffee, networking, partner exhibits.
4:00-4:30
AI-Designed Biosensors on GatorComputationally engineered reagents in practice.
Monod Bio
4:30-5:00
Gator Bio Technology ReviewLatest innovations across the BLI platform.
Sri Kumaraswamy · Gator Bio
5:00-6:00
Cocktail ReceptionDrinks, hors d'oeuvres, conversations that matter.
04 · Featured Organizations

The ecosystem.

05 · FAQ

Questions, answered.

What is Closing the Loop SF 2026? +
A focused half-day summit in South San Francisco on June 5, 2026, bringing together the teams building the AI-native discovery stack. Through keynotes and customer talks, we explore where the measurement layer sits in modern AI-bio workflows, and what loop discipline actually looks like in production.
When and where? +
June 5, 2026 · 1:00-5:00 PM PST · Timber + Tide (formerly The Lighthouse Cafe), 685 Gateway Blvd, South San Francisco, CA 94080. Cocktail reception immediately follows.
Who should attend? +
R&D leaders, AI/ML platform teams, protein engineers, and discovery operations leads working at the intersection of computation and the bench. Bay Area Big Pharma, tech-bio startups, and academic AI labs especially welcome.
Is there a registration fee? +
No. Attendance is free, but seats are limited. Registration required.
What should I bring? +
Yourself, a colleague, business cards, and questions. The rest is on us.
Will meals be provided? +
Light refreshments throughout, and a full cocktail reception with hors d'oeuvres at 4:35 PM. Dietary needs covered. Note them at registration.

Close the loop.
Be in the room.

Reserve your seat →

FREE TO ATTEND · LIMITED CAPACITY